Optical NeuroImaging Instrumentation at Clarkson University
نویسندگان
چکیده
Wide-field intrinsic optical signal (IOS) imaging is used in functional cortex mapping for its excellent spatial resolution. Extrinsic dye signals can be introduced as extrinsic optical signal (EOS) imaging to improve signal noise ratio and temporal resolution. This paper describes the wide-field IOS/EOS imaging instrumentation at Clarkson University’s Center for Rehabilitation Engineering, Science, and Technology (CREST). This equipment is used for neuroimaging purposes. This paper also discusses a novel method to enhance EOS through the use of self-assembled nano-particles as extrinsic dual-dye sensor preparations. Unique layer-by-layer fabrication processes are discussed, as is current research projects on sensors for in vivo nitric oxide imaging.
منابع مشابه
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a Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, 450 Clarkson Avenue, Box #29, Brooklyn, NY 11203, USA b Medical Department, Brookhaven National Laboratory, New York, USA c University of Florida, College of Medicine, Department of Pediatrics, Gainesville, Florida, USA d University of Miami School of Medicine, Department of Pediatrics, Miami, Fl...
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